Historically
Through the vehicle of prophecy, God throws down the gauntlet to all the other "holy books" and all the other "gods" that dare to claim the title. The God of the Bible challenged in Isaiah 41:22-23,
"Let them bring forth and show us what will happen; let them show the former things, what they were, that we may consider them, and know the latter end of them; or declare to us things to come. Show the things that are to come hereafter, that we may know that you are gods; yes, do good or do evil, that we may be dismayed and see it together."
OK, there is the challenge from the God of the Bible. No other book contains prophecy that has been fulfilled with accuracy. Consider, just for now, re-establishment of the nation of Israel. See the list of prophecies at this link... http://www.konig.org/page3.htm So historically, we can conclude that God proves both His existence, His Word as well as His dwelling in the eternal realm.
Scientifically
When it comes to the origins of life there are only two possibilities: Creation or spontaneous generation. There is no third way. Spontaneous generation was disproved hundreds of years ago, but that leads us to only one other conclusion, that of supernatural creation. - Secular Scientist, George Wald, "The Origin of Life", Scientific American May 1954
The likelihood of the formation of life from inanimate matter is one to a number with 40 thousand [zeros] after it. It is enough to bury Darwin and the whole theory of evolution. There was no primordial soup, neither on this planet nor on any other, and if the beginnings of life were not random they must therefore have been the product of purposeful intelligence. - Secular Mathematician, Sir Fredrick Hoyle, Nature Nov. 1981
Physically Seen
Look in the mirror, and contemplate your eye. Imagine the complexity of color, shape, 3D rendering, lens focus, iris light adjustment, low light adaptation, then conemplating with a "soul?" the life that is staring back at you. That you are a living being that is worth so much to God, He would send His only Son to die so that you may live with Him forever.
I mean, really, do you know what it took to even ask this question? You have a physical machine called a body that is able to use its mind to ponder the question, relay visual information from a physical world of comparable low-tech computers through the optic nerve, into the brain, with the mind to comprehend the ramifications, then transfer that thought process to an incredibly complex systems of nerves, tendons, and touch to the fingers to type the letters. This then communicates a question of the soul. The soul is something that science cannot a.) explain and b.) create. It can only mimic with unsatisfactory results. That soul is concerned for the existence of an eternal destiny beyond time and space--that there is a world beyond the physical world we see in the here and now. You are an incredible creation who has been given the free will choice to believe, or not believe. A being that can love, write poetry, paint or play works of incredible complexity and beauty. To smell, and taste, enjoy. So, like you, I set out on a path to find my Creator. It is obvious that He exists, but is He personal or an impersonal force? My answer came through the study of prophecy in the Bible. Like the DNA strand and life itself, it was hard to dispute the evidence. Now with the realization of the truth of the Bible, God made it clear that He was not only a personal God, but One who wanted to know ME, and that He knew everything about me--even the number of every hair on my head.
